Personal name meaning, lame. Roman emperor from A.D. 41 to 54. He made Judea a Roman province in A.D. 44. He expelled Jews from Rome in about A.D. 49 (Acts 18:2), probably due to conflict between Jews and Christians in Rome. Apparently his fourth wife Agrippina poisoned him in A.D. 54 and took charge of the empire for her son Nero. The prophet Agabus announced a coming famine during Claudius’ reign (Acts 11:28).